Nadiifinta Sare ee Sorbitol ee Warshadaha Dawooyinka

Hordhaca alaabta

Astaamaha jireed iyo kiimikaad ee Sorbitol
1. Jiritaanka foomka Sorbitol ee jiritaanka ugu weyn waa dareere iyo adag: dareeraha sorbitol waa 50% ama 70% aan midab lahayn xal aqueous; muuqaalka adag ee sorbitol waa irbad cad, jajab ama budada crystalline granular, qaar ka mid ah waxay ka kooban yihiin 0.5 ama 1 molecule oo biyo ah oo crystallization ah.
2. Dhadhanka iyo macaanka Sorbitol waxa uu leeyahay dhadhan gaar ah, qabow iyo dhadhamin, macaankuna waxa uu qiyaastii 60% ka yahay isku ururinta sukrose.
3. Sorbitol-ku milmay iyo viscosity waa mid aad ugu milmay biyaha, wax yar bay ku milmi karaan methanol, ethanol iyo acetic acid, iwm. Sababtoo ah milanka biyaha, sorbitol ma fududa in lagu soo saaro wax soo saarka warshadaha. Xaalado isku mid ah, viscosity of sorbitol biyaha ayaa waxyar ka hooseeya kan sukrose.
4. hygroscopicity iyo humectancy Sorbitol hygroscopicity waa mid aad u weyn, hygroscopicity aad ayuu uga weyn yahay sucrose, wax yar ka yar glycerol, hawada Kiimikadabook gaaska qaraabo qoyaan waa ka weyn yahay marka ay aad u fududahay in la nuugo caking qoyaanka; laakiin γ nooca crystalline ee sorbitol hygroscopicity waa ka yar yahay. Kordhi nolosha shelf ee alaabta.
5. Yaraynta dhibicda qaboojinta ee Sorbitol aqueous waxay keeni doontaa dhibic baraf ah, codsatay cuntada la qaboojiyey waxay ka fogaan kartaa muuqaalka barafka, waxay yareysaa joojinta crystal ama roobabka roobka, si wax ku ool ah u wanaajiso dhadhanka alaabta.
6. Xasilooni Sorbitol molecule kuma jiraan kooxaha dhimaya, guryaha kiimikaadku waa kuwo deggan, aan guban, aan kacsanayn, caabbinta aashitada iyo alkali, oo aan si fudud hawada u oksaydhnayn. Dejinta kuleylka Sorbitol waa mid wanaagsan; xaaladaha falcelinta qaarkood, sorbitol waa la fuuqbaxay karaa iyo oksaydhized, esterification, etherification iyo falcelin kale, in acid xoog leh iyo xalalka alkali sidoo kale chelate kartaa ion biraha kala duwan.
7. Cadaadiska Osmotic Miisaanka molecular Sorbitol wax yar ayuu ka weyn yahay gulukooska, markaa cadaadiska osmotic wuxuu ku dhow yahay glucose, 1.88 jeer sukrose. Cadaadiska osmotic-ga ee sarreeya macnaheedu waa in iska caabbinta noolaha ay si aad ah u xoog badan tahay, waxaana loo isticmaali karaa in lagu xakameeyo noolaha yaryar ee ku jira maraqa iyo khudradda.
Sorbitol ee warshadaha dawooyinka
Sorbitol waxaa loo isticmaali karaa sida alaabta ceeriin ee soo saarista fitamiin C; waxa kale oo loo isticmaali karaa sida alaabta ceeriin ee sharoobada, faleebooyinka la isku duro, kiniinnada daawada lagu riixo, sida kala firdhiso daroogada, filler, cryoprotectant, wakiilka anticrystallisation, xasilinta dawooyinka dhaqanka Chinese, wakiilka qoynta, plasticizer kaabsoosha, wakiilka macaan, matrix cadarka, iwm Barrett et al. waxa lagu farsameeyay polyester-ka khafiifka ah iyadoo la isticmaalayo acrylic acid sida dibasic acid oo u dooratay sorbitol sida khamriga. Tijaabooyin cytotoxicity in vitro ee Swiss albino murine 3T3 fibroblasts (SAFs) ayaa muujiyay badbaadada unugyada sare.Teng et al. loo diyaariyey poly(L-lactic acid) oo lix-gacan leh s-PLLA sida daawada siidaynta la xakameeyey ee molecules daroogada hydrophobic iyadoo la furayo polymerization ee l-lactic acid iyadoo la adeegsanayo sorbitol sida bilawga iyo caprylate stannous sida kicinta.Maniganda et al. isku dubariday hab lysosomal bartilmaameed u ah bixinta daawada si loo bixiyo dawada ka hortagga kansarka Adriamycin iyadoo la soo bandhigay octaguanidine iyo tetrapeptide taxanaha lysosomal B (CAT B) iyadoo la isticmaalayo sorbitol laf dhabarta. Maaddada la farsameeyey, xoojinta adriamycin ee ay sii daysay DDS1 ayaa ka sarraysay unugyada burooyinka marka loo eego unugyada caadiga ah iyo badeecada la farsameeyey ma muujin wax sun ah oo muhiim ah xitaa marka la eego xaddi sare.

Macluumaadka shirkadda

Waxyaalaha ay shirkadu soo dejiso iyo wax-soo-saarka dhoofinta ugu badan waxaa ka mid ah

(1) Batroolka: Wax soo saarka batroolka waa erey guud oo loogu talagalay badeecado kala duwan oo si toos ah looga soo saaro batroolka ama qayb ka mid ah batroolka. Mid ka mid ah hababka sifaynta, dildilaaca catalytic, waa isticmaalka kulaylka, cadaadiska iyo kicinta si loo jejebiyo saliidaha culus ee saliidaha fudud, badiba shidaalka.

Polymers: Polymersation waa habka ay unugyada soo noqnoqda ee ka samaysan polymer ay si wadajir ah ugu xiran yihiin bonds covalent . Polymers waxay ka jiri karaan gobolo kala duwan iyadoo ku xiran wajiga, qaabeynta iyo habeynta silsiladahooda molecular. Labada dawladood ee ugu waaweyn waa amorphous iyo crystalline. Polymers inta badan waxay ku jiraan qaab semi-crystalline ah kaas oo wejiyada amorphous iyo crystalline ay wada nool yihiin.